Celia A Schiffer: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G

Kouno, Takahide, Luengas, Elizabeth M, Shigematsu, Megumi, Shandilya, Shivender M D, Zhang, JingYing, Chen, Luan, Hara, Mayuko, Schiffer, Celia A, Harris, Reuben S, Matsuo, Hiroshi

Journal:

Nature Structural and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 2.37 MB

english, 2015

2

Synonymous mutations at the beginning of the influenza A virus hemagglutinin gene impact experimental fitness

Canale, Aneth S., Venev, Sergey V., Whitfield, Troy W., Caffrey, Daniel R., Marasco, Wayne A., Schiffer, Celia A., Kowalik, Timothy F., Jensen, Jeffrey D., Finberg, Robert W., Zeldovich, Konstantin B.

Journal:

Journal of Molecular Biology

Year:

2018

Language:

english

File:

PDF, 6.87 MB

english, 2018

3

Structural stability of disulfide mutants of basic pancreatic trypsin inhibitor: A molecular dynamics study

Schiffer, Celia A., van Gunsteren, Wilfred F.

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 753 KB

english, 1996

4

Mass spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity

Jared R. Auclair, Karin M. Green, Shivender Shandilya, James E. Evans, Mohan Somasundaran, Celia A. Schiffer

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 2.95 MB

english, 2007

5

Discovery of HIV-1 Protease Inhibitors with Picomolar Affinities Incorporating N -Aryl-oxazolidinone-5-carboxamides as Novel P2 Ligands

Ali, Akbar, Reddy, G. S. Kiran Kumar, Cao, Hong, Anjum, Saima Ghafoor, Nalam, Madhavi N. L., Schiffer, Celia A., Rana, Tariq M.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 395 KB

english, 2006

6

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

Carpenter, Michael A., Li, Ming, Rathore, Anurag, Lackey, Lela, Law, Emily K., Land, Allison M., Leonard, Brandon, Shandilya, Shivender M. D., Bohn, Markus-Frederik, Schiffer, Celia A., Brown, William

Journal:

Journal of Biological Chemistry

Year:

2012

Language:

english

File:

PDF, 1.73 MB

english, 2012

7

Mavyret: A Pan-Genotypic Combination Therapy for the Treatment of Hepatitis C Infection

Matthew, Ashley N., Kurt Yilmaz, Nese, Schiffer, Celia A.

Journal:

Year:

2017

Language:

english

File:

PDF, 383 KB

english, 2017

8

Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes

Cai, Erica P., Ishikawa, Yuki, Zhang, Wei, Leite, Nayara C., Li, Jian, Hou, Shurong, Kiaf, Badr, Hollister-Lock, Jennifer, Yilmaz, Nese Kurt, Schiffer, Celia A., Melton, Douglas A., Kissler, Stephan,

Journal:

Nature Metabolism

Year:

2020

File:

PDF, 7.62 MB

2020

9

Accessibility and order of water sites in and around proteins: A crystallographic time-averaging study

Celia A. Schiffer, Wilfred F. van Gunsteren

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 381 KB

english, 1999

10

PTEN enters the nucleus by diffusion

Fenghua Liu, Stefan Wagner, Robert B. Campbell, Jeffrey A. Nickerson, Celia A. Schiffer, Alonzo H. Ross

Journal:

Journal of Cellular Biochemistry

Year:

2005

Language:

english

File:

PDF, 392 KB

english, 2005

11

Combating Susceptibility to Drug Resistance: Lessons from HIV-1 Protease

Nancy M. King, Moses Prabu-Jeyabalan, Ellen A. Nalivaika, Celia A. Schiffer

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 330 KB

english, 2004

12

The role of protein-solvent interactions in protein unfolding

Celia A Schiffer, Volker Dötsch

Journal:

Current Opinion in Biotechnology

Year:

1996

Language:

english

File:

PDF, 527 KB

english, 1996

13

Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket

Hui Liu, Padhma Radhakrishnan, Loranne Magoun, Moses Prabu, Kenneth G. Campellone, Pamela Savage, Feng He, Celia A. Schiffer, John M. Leong

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 433 KB

english, 2002

14

Inclusion of solvation free energy with molecular mechanics energy: Alanyl dipeptide as a test case

Celia A. Schiffer, James W. Caldwell, Robert M. Stroud, Peter A. Kollman

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 467 KB

english, 1992

15

Expression, purification, and characterization of thymidylate synthase from Lactococcus lactis

Patricia J. Greene, Pak-Lam Yu, Jia Zhao, Celia A. Schiffer, Daniel Santi

Journal:

Protein Science

Year:

1994

Language:

english

File:

PDF, 1.22 MB

english, 1994

16

Cooperative fluctuations of unliganded and substrate-bound HIV-1 protease: A structure-based analysis on a variety of conformations from crystallography and molecular dynamics simulations

Nese Kurt, Walter R.P. Scott, Celia A. Schiffer, Turkan Haliloglu

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2003

Language:

english

File:

PDF, 994 KB

english, 2003

17

Substrate specificity in HIV-1 protease by a biased sequence search method

Nevra Ozer, Turkan Haliloglu, Celia A. Schiffer

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2006

Language:

english

File:

PDF, 222 KB

english, 2006

18

Evaluation of the substrate envelope hypothesis for inhibitors of HIV-1 protease

Sripriya Chellappan, Visvaldas Kairys, Miguel X. Fernandes, Celia Schiffer, Michael K. Gilson

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 695 KB

english, 2007

19

Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 protease

Michael D. Altman, Ellen A. Nalivaika, Moses Prabu-Jeyabalan, Celia A. Schiffer, Bruce Tidor

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 520 KB

english, 2008

20

Prediction of homologous protein structures based on conformational searches and energetics

Celia A. Schiffer, James W. Caldwell, Peter A. Kollman, Dr. Robert M. Stroud

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1990

Language:

english

File:

PDF, 1.14 MB

english, 1990

21

Investigations of peptide hydration using NMR and molecular dynamics simulations: A study of effects of water on the conformation and dynamics of antamanide

Jeffrey W. Peng, Celia A. Schiffer, Ping Xu, Wilfred F. van Gunsteren, Richard R. Ernst

Journal:

Journal of Biomolecular NMR

Year:

1996

Language:

english

File:

PDF, 1.91 MB

english, 1996

22

Toward the Design of Mutation-Resistant Enzyme Inhibitors: Further Evaluation of the Substrate Envelope Hypothesis

Visvaldas Kairys, Michael K. Gilson, Viney Lather, Celia A. Schiffer, Miguel X. Fernandes

Journal:

Chemical Biology & Drug Design

Year:

2009

Language:

english

File:

PDF, 441 KB

english, 2009

23

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

Chen, Weijun, Lam, Suvana S, Srinath, Hema, Jiang, Zhaozhao, Correia, John J, Schiffer, Celia A, Fitzgerald, Katherine A, Lin, Kai, Royer Jr, William E

Journal:

Nature Structural and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

24

Lack of synergy for inhibitors targeting a multi-drug-resistant HIV-1 protease

Nancy M. King, Laurence Melnick, Moses Prabu-Jeyabalan, Ellen A. Nalivaika, Shiow-Shong Yang, Yun Gao, Xiaoyi Nie, Charles Zepp, Donald L. Heefner, Celia A. Schiffer

Journal:

Protein Science

Year:

2002

Language:

english

File:

PDF, 1.23 MB

english, 2002

25

Design, Synthesis, and Biological and Structural Evaluations of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance

Parai, Maloy Kumar, Huggins, David J., Cao, Hong, Nalam, Madhavi N. L., Ali, Akbar, Schiffer, Celia A., Tidor, Bruce, Rana, Tariq M.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.07 MB

english, 2012

26

Structural, kinetic, and thermodynamic studies of specificity designed HIV-1 protease

Oscar Alvizo, Seema Mittal, Stephen L. Mayo, Celia A. Schiffer

Journal:

Protein Science

Year:

2012

Language:

english

File:

PDF, 780 KB

english, 2012

27

Quantitative comparison of errors in15N transverse relaxation rates measured using various CPMG phasing schemes

Wazo Myint, Yufeng Cai, Celia A. Schiffer, Rieko Ishima

Journal:

Journal of Biomolecular NMR

Year:

2012

Language:

english

File:

PDF, 920 KB

english, 2012

28

The challenge of developing robust drugs to overcome resistance

Amy C. Anderson, Michael P. Pollastri, Celia A. Schiffer, Norton P. Peet

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 768 KB

english, 2011

29

Hydrophobic Sliding: A Possible Mechanism for Drug Resistance in Human Immunodeficiency Virus Type 1 Protease

Jennifer E. Foulkes-Murzycki, Walter Robert Peter Scott, Celia A. Schiffer

Journal:

Year:

2007

Language:

english

File:

PDF, 1.64 MB

english, 2007

30

Erratum to “Covariation of amino acid positions in HIV-1 protease” [Virology 314 (2003) 536–548]

Noah G. Hoffman, Celia A. Schiffer, Ronald Swanstrom

Journal:

Year:

2005

Language:

english

File:

PDF, 212 KB

english, 2005

31

Co-evolution of nelfinavir-resistant HIV-1 protease and the p1–p6 substrate

Madhavi Kolli, Stephane Lastere, Celia A. Schiffer

Journal:

Year:

2006

Language:

english

File:

PDF, 361 KB

english, 2006

32

Covariation of amino acid positions in HIV-1 protease

Noah G. Hoffman, Celia A. Schiffer, Ronald Swanstrom

Journal:

Year:

2003

Language:

english

File:

PDF, 510 KB

english, 2003

33

Curling of Flap Tips in HIV-1 Protease as a Mechanism for Substrate Entry and Tolerance of Drug Resistance

Walter R.P Scott, Celia A Schiffer

Journal:

Year:

2000

Language:

english

File:

PDF, 986 KB

english, 2000

34

Substrate Shape Determines Specificity of Recognition for HIV-1 Protease: Analysis of Crystal Structures of Six Substrate Complexes

Moses Prabu-Jeyabalan, Ellen Nalivaika, Celia A. Schiffer

Journal:

Year:

2002

Language:

english

File:

PDF, 504 KB

english, 2002

35

Nitric Oxide-Mediated Inhibition of Hdm2−p53 Binding†

Schonhoff, Christopher M., Daou, Marie-Claire, Jones, Stephen N., Schiffer, Celia A., Ross, Alonzo H.

Journal:

Year:

2002

Language:

english

File:

PDF, 231 KB

english, 2002

36

Extreme Entropy–Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease

King, Nancy M., Prabu-Jeyabalan, Moses, Bandaranayake, Rajintha M., Nalam, Madhavi N. L., Nalivaika, Ellen A., Özen, Ayşegül, Haliloǧlu, Türkan, Yılmaz, Neşe Kurt, Schiffer, Celia A.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 4.70 MB

english, 2012

37

Design and Synthesis of HIV-1 Protease Inhibitors Incorporating Oxazolidinones as P2/P2‘ Ligands in Pseudosymmetric Dipeptide Isosteres

Reddy, G. S. Kiran Kumar, Ali, Akbar, Nalam, Madhavi N. L., Anjum, Saima Ghafoor, Cao, Hong, Nathans, Robin S., Schiffer, Celia A., Rana, Tariq M.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 458 KB

english, 2007

38

Simultaneous Refinement of the Structure of BPTI Against NMR Data Measured in Solution and X-ray Diffraction Data Measured in Single Crystals

Celia A. Schiffer, Robert Huber, Kurt Wüthrich, Wilfred F. van Gunsteren

Journal:

Journal of Molecular Biology

Year:

1994

File:

PDF, 637 KB

1994

39

How does a symmetric dimer recognize an asymmetric substrate? a substrate complex of HIV-1 protease

Moses Prabu-Jeyabalan, Ellen Nalivaika, Celia A Schiffer

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 723 KB

english, 2000

40

Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites

Celia Schiffer, Mark Ultsch, Scott Walsh, William Somers, Abraham M de Vos, Anthony Kossiakoff

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

41

Contribution of Ser386 and Ser396 to Activation of Interferon Regulatory Factor 3

Weijun Chen, Hema Srinath, Suvana S. Lam, Celia A. Schiffer, William E. Royer Jr, Kai Lin

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.20 MB

english, 2008

42

Dynamics of Preferential Substrate Recognition in HIV-1 Protease: Redefining the Substrate Envelope

Ayşegül Özen, Türkan Haliloğlu, Celia A. Schiffer

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 3.22 MB

english, 2011

43

Structure-Based Prediction of Potential Binding and Nonbinding Peptides to HIV-1 Protease

Kurt, Nese, Haliloglu, Turkan, Schiffer, Celia A.

Journal:

Biophysical Journal

Year:

2003

Language:

english

File:

PDF, 290 KB

english, 2003

44

Crystallization of human thymidylate synthase

Celia A. Schiffer, V.Jo Davisson, Daniel V. Santi, Robert M. Stroud

Journal:

Journal of Molecular Biology

Year:

1991

Language:

english

File:

PDF, 1.06 MB

english, 1991

45

Rationale for More Diverse Inhibitors in Competition with Substrates in HIV-1 Protease

Ozer, Nevra, Schiffer, Celia A., Haliloglu, Turkan

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 1.61 MB

english, 2010

46

Structural Insights into Calmodulation of Neuronal KCNQ Channels

Mruk, Karen, Shandilya, Shivender M.D., Blaustein, Robert O., Schiffer, Celia A., Kobertz, William R.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

47

Cooperative Effects of Drug-Resistance Mutations in the Flap Region of HIV-1 Protease

Foulkes-Murzycki, Jennifer E., Rosi, Christina, Kurt Yilmaz, Nese, Shafer, Robert W., Schiffer, Celia A.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 303 KB

english, 2013

48

Protein Structure Prediction with a Combined Solvation Free Energy-Molecular Mechanics Force Field

Schiffer, Celia A., Caldwell, James W., Kollman, Peter A., Stroud, Robert M.

Journal:

Molecular Simulation

Year:

1993

Language:

english

File:

PDF, 5.18 MB

english, 1993

49

Evaluating the Role of Macrocycles in the Susceptibility of Hepatitis C Virus NS3/4A Protease Inhibitors to Drug Resistance

Ali, Akbar, Aydin, Cihan, Gildemeister, Reinhold, Romano, Keith P., Cao, Hong, Özen, Ayşegül, Soumana, Djade, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Schiffer, Celia A.

Journal:

ACS Chemical Biology

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

50

Decomposing the Energetic Impact of Drug Resistant Mutations in HIV-1 Protease on Binding DRV

Cai, Yufeng, Schiffer, Celia A.

Journal:

Journal of Chemical Theory and Computation

Year:

2010

Language:

english

File:

PDF, 4.36 MB

english, 2010